He currently plays for Once Caldas (w), wearing the number 10 shirt. He plays primarily as a Forward. He stands at 165cm tall and weighs 55kg.

In the UEFA Women's Champions League 2024-2025 season, Vanessa Franco Giraldo scored 0 goals and provided 0 assists across 1 appearances, averaging 0 goals per game with 0 shots attempted and 0 on target.