He currently plays for Independiente Santa Fe (W), wearing the number 8 shirt. At the international level, he represents Colombia Women. He plays primarily as a Midfield.

Across 2 appearances in the Colombian Liga Betplay Femenina 2024, Juana Sofía Ortegón Giraldo registered 0 goals and 0 assists, while completing 0 key passes out of 0 total passes with a passing accuracy of -.