He currently plays for Accra Hearts of Oak, wearing the number 15 shirt. He plays primarily as a Defender. His current market value is estimated at 75K €.

His most recent move was a Free from King Faisal to Accra Hearts of Oak on 2023-09-22.

Throughout the CAF African Olympic (Preliminaries) 2022-2023, David Oppong Afrane featured in 3 matches, averaging 2.7 tackles, 1.3 interceptions, and 4 clearances per game, while blocking 0.3 shots per game.