Match: Serie A
Fixture: Inter Milan vs Roma
Local Kick-off Time: Apr 5, 2026 7.45pm
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Prediction: Roma Draw or Win
Roma are battling for Champions League qualification this season. The team, which struggled last season, has regained form and shown great tenacity under Gian Piero Gasperini.
Inter Milan have failed to secure a win in three consecutive games, with AC Milan and Napoli closing the points gap. Key centre-back Alessandro Bastoni and forward Pio Esposito made costly mistakes for Italy in the World Cup qualifier against Bosnia and Herzegovina in midweek, and their mental recovery remains uncertain.
The Asian handicap sets Inter Milan at -0.75 goals at home, but Roma are a tough opponent for Inter to cover this line based on their performances against top teams in Serie A and the Champions League this season. We back Roma to stay unbeaten away.
Comprehensive Prediction Analysis:
Inter Milan
Since beating Juventus in the most recent Derby d'Italia, Inter have struggled to match their high standards in three separate competitions - coinciding with the absence of inspirational skipper Lautaro Martinez.
Back-to-back defeats against Bodo/Glimt sent them crashing out of the Champions League, then they beat Genoa and played out a goalless cup draw with Como but subsequently lost to Milan in the Derby della Madonnina. Cristian Chivu's side were then denied by a late leveller against Atalanta, before going three league games without a win for the first time since April 2023.
Before international football intervened, the Nerazzurri let an early lead slip against relegation-threatened Fiorentina at Stadio Franchi, ultimately settling for a 1-1 draw.
As a result, their once formidable lead at the Serie A summit has been cut down to six points, and even reigning champions Napoli have moved to within seven of top spot. Nonetheless, Chivu's first campaign could yet end with a rare domestic double: Inter's Coppa Italia semi-final against Como will conclude with the home leg later this month.
Despite a dip in their proud European record, domestically they have remained tough to beat on home soil this season, posting 11 wins, two draws and just two losses in Serie A.
Now, one day before Milan and Napoli clash in Campania, Inter will aim to get back on track by beating Roma, who they edged 1-0 in October's reverse fixture.
Roma
After previously struggling at San Siro, Roma have actually won two of their last three away games against Inter before heading into this crucial contest: Matias Soule scored the Giallorossi's winner there just under a year ago.
Recovering from a painful Europa League exit to domestic rivals Bologna, they recently signed off for the international break by beating Lecce 1-0 and ended a costly five-match winless streak.
That result left them alongside Juventus on 54 points, just three behind fourth-placed Como in a frantic race for Italy's final Champions League spot - but they now face a difficult run-in.
Set to meet Atalanta, Fiorentina, Bologna again, and old foes Lazio before the end of term, Roma will hit the home straight with perhaps the toughest test of all.
Head coach Gian Piero Gasperini - who had a short, ill-fated spell as Inter boss several years ago - has personally lost more matches against the Nerazzurri than anyone else: 18 of 32 meetings so far. Furthermore, his current club have accrued 10 points fewer on the road compared to 32 in
front of their own fans, and Roma's last away win across all competitions dates back to January.
In fact, seven of the capital club's 10 league defeats have come from away fixtures, making their long journey north one to be feared rather than anticipated.
Final Prediction:
Asian Handicap: Roma +0.75
European Handicap: Away Draw or Win
Predicted Scores: 1-2, 2-2, 2-3
Predicted Total Goals: 3, 4, 5
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